Randy M. Dumse of New Micros
sent us a link to a Science
Daily article on a breakthrough in the understanding of human
long term memory. Researchers at SUNY Downstate Medical Center including
Andre A.
Fenton and Todd C.
Sacktor have discovered the molecular mechanism that maintains long
term memories. An enzyme known as protein kinase M zeta maintains
memories by persistently strengthening synaptic connections between
neurons. Blocking the enzyme erases the associated memory. Removing the
block allows new long term memories to be stored. The discovery could
lead to a method of selectively erasing human memories
as easily "as you might erase a computer disc". The researchers
suggest using selective erasure to treat neuropathic pain, dystonia, or
post-traumatic stress. They don't mention the dozens of ethically
problematic uses of memory manipulation that have been explored in
science fiction. Let's see, Philip K. Dick's Paycheck
suggests erasing memories of employees who do reverse engineering. In
the film Eternal
Sunshine of the Spotless Mind, characters erase memories of bad
relationships. I've lost count of how many times crews of
the Starships Enterprise had their memories wiped, replaced, or
manipulated. What about a memory bomb that erases the
memories of your enemies? This discovery should have the ethics
department working
overtime. For more information on the research see the SUNY
news release or the abstract
for their paper.
Fascinating discovery,got to look into this new discovery and story
further but initial thoughts are about removing bad memories/post
traumatic stress memories,filling the patients minds with a void then
as a result victims of tradegy/crime people could within a few months
be free of the expierience and back to normality for the rest of their
lives.By removing the bad memories of people that have only learnt to
fight and battle (as in other countries especially) then you could
regain just societies and hopes in places where there (especially
recently) has be proven to be no real understanding of this,resulting
in the probable future of a return to chaos and fighting.Also there is
the point about zeta and neurons that are artificial being implanted
into robots so that machines have a memory,are able to learn and adapt
and ANSWER the whole question about living learning machines,that
progress/evolve by themselves,may well do another reply on
this,cheers.
Keep in mind that the quote you cite was written by the author of the
article and not the researchers themselves. Even though our grasp of
neurochemistry is improving, our ability to execute chemical changes on
a microscopic level is still in its infancy. For example, the
neurochemistry of Tourette Syndrome has been under constant research for
the past thirty years, and the chemistry itself is increasingly
well-understood. But treatment still equates to flooding the entire
brain with a carefully titrated mix of neurotransmitters and inhibitors.
To apply this same model to this new discovery, a closer analogy would
be that we could erase someone's memory like degaussing the entire disk
rather than just deleting selected files.
More exciting to me than the ability to erase memories is the ability to
understand and potentially slow or stop processes that are already doing
this. I'm glad the article mentioned the potential impact on treatment
of Alzheimer's. There are scads of conditions that can cause long term
memory loss. If this can help us understand the mechanisms behind them,
that's exciting.
And yes, there are some serious ethical questions involved with this
discovery, not the least being what a hospital would do if someone was
inadvertently wiped. But there are always ethical questions attached to
discovery. It's what we choose to do with the things we learn that
define who we are.
Maybe to stop alzheimers in all people the chemicals just need to be
kept constant as when the person was younger,to cure it through just
stopping the lesser flow associated with age.This must also apply to
many other conditions like you just mentioned and when the mind is
functioning properly the body hosting these conditions can get itself
togeather.So basicaly the initial part of all the learning about this
new brain memory process should be the simple bit about keeping this
chemical reacting with the neurons at all stages of life.....No
Alzheimers then.